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The Roto-Mini™ series of rotating mixers provide a wide range of mixing capabilities. Suitable for an array of laboratory applications including resuspension, protein binding, nucleic acid purification, etc. the mixers include interchangeable tube holders for accommodating all common tube sizes from 0.5 mL to 50 mL. The motion can be adjusted from vertical (end over end) mixing, to horizontal (rolling or hybridization style) mixing.